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Translational Medicine / 转化医学Metaplastic Breast Cancer, Rare Breast Histologies

Elisabetta Munzone

MD

🏢Istituto Europeo di Oncologia (IEO)🌐Italy

Head, Division of Medical Senology

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Key Contributions

👥Biography 个人简介

Elisabetta Munzone is a breast oncologist with specialized expertise in rare and aggressive histologic subtypes including metaplastic breast carcinoma, a highly chemoresistant TNBC variant characterized by sarcomatoid differentiation and PI3K pathway activation. She has led retrospective analyses and prospective studies evaluating checkpoint inhibitor combinations, PI3K/mTOR inhibitors, and novel agents in metaplastic breast cancer, a disease for which standard TNBC chemotherapy regimens perform poorly. She has contributed to international guidelines on rare breast cancer histologies.

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🧪Research Fields 研究领域

metaplastic breast carcinoma treatment
spindle cell breast sarcomatoid
chemotherapy-resistant rare breast cancer
PI3K pathway metaplastic breast
immunotherapy triple-negative rare subtypes

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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