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Translational Medicine / 转化医学Immunotherapy, Predictive Biomarkers

Eliezer Van Allen

MD

🏢Dana-Farber Cancer Institute / Harvard Medical School🌐USA

Associate Professor of Medicine; Associate Director, Center for Cancer Genomics

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👥Biography 个人简介

Eliezer Van Allen applies machine learning and computational genomics to develop predictive models for immunotherapy response, including whole-exome sequencing-based biomarkers predicting anti-PD-1 benefit across tumor types. His landmark studies have revealed genomic determinants of IO response and resistance including tumor mutational burden, BRCA mutations, and epigenetic biomarkers. He contributes to the Foundation for Precision Cancer Medicine and leads translational genomics programs across multiple tumor types. Van Allen is one of the most innovative computational oncologists working at the interface of genomics, immunology, and clinical IO.

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🧪Research Fields 研究领域

genomic IO biomarkers
machine learning immunotherapy response
WES tumor immunotherapy prediction
neoantigen load IO
germline cancer genomics immunotherapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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