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Translational Medicine / 转化医学Lung Cancer, First-Line Immunotherapy

Edward Garon

MD

🏢UCLA Jonsson Comprehensive Cancer Center🌐USA

Director, Thoracic Oncology Program; Professor of Medicine

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👥Biography 个人简介

Edward Garon contributed to the foundational KEYNOTE-001 study in lung cancer that established PD-L1 as a predictive biomarker and supported pembrolizumab approval. His research helped define the optimal PD-L1 cut-points for immunotherapy benefit in NSCLC and continues to explore novel first-line IO strategies. He leads a robust thoracic oncology clinical trials program at UCLA spanning immunotherapy combinations and targeted agents. Garon's early clinical work contributed directly to the clinical development path that yielded the first PD-1 approval in lung cancer.

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🧪Research Fields 研究领域

KEYNOTE-001 lung pembrolizumab
PD-L1 testing validation
nivolumab squamous NSCLC
first-line IO NSCLC early development
lung IO clinical trial

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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