Learn more →
Back to Expert Scholars
Translational Medicine / 转化医学T Cell Exhaustion, Transcriptional and Epigenetic Programs

E. John Wherry

PhD

🏢University of Pennsylvania Perelman School of Medicine🌐USA

Director, Institute for Immunology

130
h-index
0
Key Papers
0
Key Contributions

👥Biography 个人简介

E. John Wherry pioneered the molecular characterization of CD8 T cell exhaustion and its epigenetic basis. His work defined TOX as a master regulator of the exhausted state and revealed limits to PD-1 reinvigoration. He continues to translate exhaustion biology into next-generation immunotherapies.

Share:

🧪Research Fields 研究领域

T cell exhaustion
PD-1
TOX
epigenetic exhaustion
checkpoint blockade

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

关注 E. John Wherry 的研究动态

Follow E. John Wherry's research updates

留下邮箱,当我们发布与 E. John Wherry(University of Pennsylvania Perelman School of Medicine)相关的新研究或访谈时,我们会通知你。

我们不会泄露你的信息,也不会发送无关内容。随时可以退订。

Explore More Experts

Discover the researchers shaping the future of cancer treatment