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Translational Medicine / 转化医学mRNA Modification Nobel, Lipid Nanoparticles

Drew Weissman

MD, PhD

🏢University of Pennsylvania🌐USA

Roberts Family Professor in Vaccine Research

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👥Biography 个人简介

Drew Weissman shared the 2023 Nobel Prize in Physiology or Medicine with Katalin Kariko for the discovery of modified mRNA that enabled modern mRNA vaccines and therapeutics. His laboratory co-invented pseudouridine-modified mRNA and lipid nanoparticle formulations that deliver mRNA effectively to target cells including antigen-presenting cells. His work directly enabled personalized mRNA cancer vaccines by solving the fundamental delivery and innate immune activation challenges. He continues to advance mRNA optimization strategies for cancer vaccine and other therapeutic applications.

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🧪Research Fields 研究领域

mRNA modification
lipid nanoparticle delivery
mRNA vaccines
nucleoside chemistry
Nobel Prize 2023

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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