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Translational Medicine / 转化医学Milestone Cancer Immunology, mRNA Cancer Vaccines

Drew Weissman

MD, PhD

🏢University of Pennsylvania Perelman School of Medicine🌐USA

Roberts Family Professor in Vaccine Research

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👥Biography 个人简介

Dr. Drew Weissman co-developed the pseudouridine modification of mRNA that enables its delivery without triggering innate immune responses, a discovery awarded the 2023 Nobel Prize in Physiology or Medicine shared with Katalin Kariko. His mRNA technology platform underpins not only COVID-19 vaccines but also the emerging field of mRNA cancer vaccines including personalized neoantigen-based mRNA immunotherapy. His work has launched a new era in cancer vaccine development leveraging lipid nanoparticle-delivered mRNA.

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🧪Research Fields 研究领域

mRNA technology modified nucleosides
mRNA cancer vaccine development
pseudouridine mRNA innate immune evasion
BNT111 mRNA melanoma vaccine
lipid nanoparticle mRNA delivery

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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