Dominique Elias
多米尼克·埃利亚斯
MD, PhD
Professor of Surgery; Senior Surgical Oncologist外科学教授；高级外科肿瘤学家
👥Biography 个人简介
Dominique Elias is a senior surgical oncologist at Institut Gustave Roussy and a leading authority on colorectal peritoneal metastases. He has pioneered combined liver and peritoneal metastasectomy, HIPEC regimens, and early-intervention strategies for synchronous peritoneal disease. His prolific research has shaped French and European guidelines on the multimodal management of advanced colorectal cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Combined Liver and Peritoneal Metastasectomy
Demonstrated that simultaneous resection of liver and peritoneal metastases from colorectal cancer can achieve long-term survival in selected patients, expanding curative-intent surgery to patients previously considered ineligible.
Prophylactic HIPEC for High-Risk Colorectal Cancer
Led studies examining prophylactic second-look surgery with HIPEC in high-risk colorectal cancer patients, evaluating whether early treatment of occult peritoneal disease improves survival outcomes.
Prognostic Factors in Colorectal Peritoneal Carcinomatosis
Published seminal analyses of prognostic variables determining survival after CRS + HIPEC in colorectal peritoneal metastases, including PCI thresholds and the impact of nodal disease on outcomes.
Representative Works 代表性著作
Complete cytoreductive surgery plus intraperitoneal chemohyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin
Journal of Clinical Oncology (2004)
Established oxaliplatin-based HIPEC protocol outcomes at Gustave Roussy, demonstrating feasibility and survival benefit in colorectal peritoneal carcinomatosis.
Simultaneous peritoneal and liver metastases from colorectal cancer: is there a curative surgery?
Annals of Oncology (2007)
Demonstrated curative potential of combined hepatic and peritoneal resection, supporting aggressive multimodal surgery in selected patients.
Second-look surgery plus HIPEC in asymptomatic patients presenting with peritoneal carcinomatosis risk factors
Annals of Surgical Oncology (2011)
Prospective study of prophylactic second-look CRS + HIPEC strategy in high-risk colorectal cancer, informing ongoing trials of early peritoneal intervention.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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