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Translational Medicine / 转化医学Biliary Tract Cancer Korea, Gemcitabine Cisplatin IO

Do-Youn Oh

MD, PhD

🏢Seoul National University Hospital🌐Korea

Professor of Internal Medicine

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Key Contributions

👥Biography 个人简介

Do-Youn Oh is a leading Korean oncologist specializing in biliary tract cancers who contributed to the TOPAZ-1 trial establishing durvalumab plus gemcitabine and cisplatin as a new first-line standard for advanced biliary tract cancers including intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder cancer. His research has characterized the molecular epidemiology of biliary tract cancers in Korean and broader East Asian populations, including FGFR2 fusions and IDH1 mutations in intrahepatic cholangiocarcinoma and HER2 amplifications in gallbladder cancer. He has participated in pivotal trials of targeted therapies including pemigatinib and ivosidenib for FGFR2-fused and IDH1-mutated cholangiocarcinoma in Asian populations. His contributions to the Asia-Pacific biliary cancer research network have advanced clinical trial conduct and access to innovative therapies in East Asia.

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🧪Research Fields 研究领域

biliary tract cancer immunotherapy
gemcitabine cisplatin durvalumab BTC
TOPAZ-1 trial biliary cancer
cholangiocarcinoma Korean patients
intrahepatic cholangiocarcinoma IDH FGFR Korea

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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