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Translational Medicine / 转化医学Minimal Residual Disease Detection

Maximilian Diehn

MD, PhD

🏢Stanford University School of Medicine🌐USA

Professor of Radiation Oncology

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👥Biography 个人简介

Maximilian Diehn co-invented CAPP-Seq (Cancer Personalized Profiling by deep Sequencing), a highly sensitive ctDNA detection method that has become a foundational technology for MRD assessment in lung cancer and other solid tumors. His research has demonstrated that ctDNA dynamics during and after radiation therapy predict treatment response and recurrence with high accuracy. He leads clinical studies integrating MRD detection into radiation oncology treatment planning and surveillance protocols.

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🧪Research Fields 研究领域

CAPP-Seq technology
Lung cancer ctDNA
Radiation therapy MRD
Ultrasensitive sequencing
Tumor-informed MRD assays

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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