Diana Mitrea

Diana Mitrea has advanced understanding of nucleolar organization through phase separation, particularly how NPM1 mutations in acute myeloid leukemia disrupt nucleolar condensate architecture. Her work on the multilayered liquid-like structure of the nucleolus has revealed how perturbation of ribosome biogenesis condensates triggers stress responses exploitable in cancer therapy. She has developed novel biophysical approaches to study condensate organization in living cells.