Dennis Slamon

Dennis Slamon is one of the most influential oncologists of the modern era, best known for pioneering the development of trastuzumab (Herceptin) for HER2-positive breast cancer. He characterized the clinical importance of HER2 amplification in breast cancer and led clinical trials that established trastuzumab as a practice-changing therapy. He subsequently became a leading advocate and contributor to CDK4/6 inhibitor development. His lifelong research program has translated basic discoveries into treatments that have saved hundreds of thousands of lives.