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Translational Medicine / 转化医学NTRK and Rare Gene Fusions

George Demetri

MD

🏢Dana-Farber Cancer Institute🌐USA

Director, Sarcoma Center

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Key Papers
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Key Contributions

👥Biography 个人简介

George Demetri has been instrumental in establishing the tumor-agnostic paradigm for NTRK fusion-positive cancers through his work on kinase inhibitor development. His expertise in sarcoma and rare tumors has contributed to cross-histology clinical trial design for TRK-targeted agents. He is a pioneer in molecular classification of rare cancers.

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🧪Research Fields 研究领域

NTRK fusions
Tumor-agnostic therapy
Sarcoma
Kinase inhibitors
Rare cancer subtypes

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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