David Weinstock
大卫·温斯托克
MD
Associate Professor of Medicine, Harvard Medical School哈佛医学院医学副教授
👥Biography 个人简介
Expert in oncology drug resistance in lymphoma and genomic mechanisms of cancer therapy failure. Investigates how genomic alterations in lymphoma drive resistance to targeted therapies and immunotherapy, with specific focus on DLBCL and follicular lymphoma resistance to BCL-2 inhibitors and PI3K pathway agents.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Lymphoma Drug Resistance and Genomics
Characterized genomic mechanisms of resistance to BCL-2 inhibitors and PI3K pathway inhibitors in aggressive B-cell lymphomas, identifying recurrent resistance mutations and defining rational co-targeting strategies to prevent and overcome resistance.
Representative Works 代表性著作
ATM mutations in the cancer genome
Cancer Cell (2010)
Defined the landscape of ATM mutations in lymphoma and other cancers, revealing ATM loss as a driver of genomic instability and therapeutic vulnerability.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
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