David Vaux
MBBS PhD
Professor and Joint Division Head
👥Biography 个人简介
David Vaux co-discovered the role of BCL-2 in inhibiting apoptosis, a breakthrough that established BCL-2 as an oncogene rather than a classical growth-promoting factor. His work demonstrated that t(14;18) translocation in follicular lymphoma drives cancer by blocking programmed cell death rather than by increasing proliferation. He also contributed to identification of the conserved cell death machinery across species. This foundational work enabled the development of BCL-2 inhibitors now used in clinical practice.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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