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Translational Medicine / 转化医学Cancer Metabolism Milestones, mTOR Pathway
David Sabatini
MD, PhD
🏢Independent🌐USA
Independent Investigator
175
h-index
0
Key Papers
0
Key Contributions
👥Biography 个人简介
David Sabatini discovered key components of mTORC1 and how the complex senses amino acids via Rag GTPases at the lysosome. His work revolutionized understanding of growth control in cancer. mTOR-targeted therapies remain a cornerstone of modern oncology.
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🧪Research Fields 研究领域
mTORC1
amino acid sensing
Rag GTPases
lysosomal signaling
cancer metabolism
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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