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radiation-oncology / radiation-oncologySBRT Lung Cancer

David Raben

大卫·拉本

MD

🏢University of Colorado School of Medicine(科罗拉多大学医学院)🌐USA

Professor, Department of Radiation Oncology; Head and Neck/Lung Disease Group Leader放射肿瘤学系教授;头颈部/肺部疾病组长

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

David Raben is a radiation oncologist and translational researcher at the University of Colorado Cancer Center specializing in SBRT for thoracic malignancies and molecularly targeted radiosensitization. He has translated EGFR and VEGFR inhibitor findings into cooperative group clinical trials.

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🧪Research Fields 研究领域

Radiation Oncology放射肿瘤学
SBRT立体定向体部放疗
Lung Cancer肺癌
Head and Neck Cancer头颈部癌症
EGFR RadiosensitizationEGFR靶向放射增敏

🎓Key Contributions 主要贡献

SBRT for Thoracic Malignancies

Advanced SBRT dose-fractionation protocols for early-stage and central lung tumors, contributing to national practice guidelines.

EGFR Inhibitor + Radiation Synergy

Led preclinical and clinical studies demonstrating synergy between EGFR inhibitors and radiation in head and neck and lung cancer.

NRG/RTOG Cooperative Trials

Co-developed multi-institutional clinical trials testing molecularly targeted radiosensitization in thoracic and head and neck malignancies.

Representative Works 代表性著作

[1]

Antitumor activity of ZD6474 combined with radiation in preclinical lung cancer models

Clinical Cancer Research (2004)

Demonstrated VEGFR inhibition plus radiation produces supra-additive tumor growth delay in preclinical lung models.

[2]

RTOG 0617: randomized phase III comparison of high-dose vs standard-dose RT for NSCLC

Journal of Clinical Oncology (2015)

Landmark trial contributing to dose prescribing standards in locally advanced NSCLC.

🏆Awards & Recognition 奖项与荣誉

🏆ASTRO Fellow
🏆University of Colorado Outstanding Mentor Award
🏆Lung Cancer Research Foundation Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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