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Translational Medicine / 转化医学Pre-metastatic Niche, Exosomes
David Lyden
MD, PhD
🏢Weill Cornell Medicine🌐USA
Professor of Pediatrics and Cell Biology
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Key Contributions
👥Biography 个人简介
David Lyden discovered the pre-metastatic niche and defined how tumor-derived exosomes with specific integrins determine organ-specific metastasis. His work transformed understanding of metastatic organotropism through exosomal education of distant organs.
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🧪Research Fields 研究领域
pre-metastatic niche
exosome organotropism
tumor-derived vesicles
integrin exosome
metastasis education
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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