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Translational Medicine / 转化医学Oncolytic Virus, NDV Newcastle Disease Virus

David Kirn

MD

🏢Imvax Inc.🌐USA

Chief Medical Officer, Imvax Inc.

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👥Biography 个人简介

David Kirn has been a pioneering figure in oncolytic virus clinical development for over two decades, including early work on ONYX-015 adenovirus and the poxvirus-based JX-594 (pexastimogene devacirepvec) in hepatocellular carcinoma. He has also developed the Imvax glioblastoma platform leveraging intratumoral antigen exposure for systemic vaccine induction. His career bridges the foundational clinical translation of oncolytic viruses from bench to bedside.

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🧪Research Fields 研究领域

Newcastle disease virus NDV oncolytic
poxvirus oncolytic JX-594
oncolytic virus clinical development history
intravenous oncolytic virus pharmacology
IMVax GBM intradermal vaccine

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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