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Translational Medicine / 转化医学Lung Cancer, KRAS G12C

David Gandara

MD

🏢UC Davis Comprehensive Cancer Center🌐USA

Professor of Medicine and Director Emeritus, Thoracic Oncology Program

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Key Contributions

👥Biography 个人简介

Dr. David Gandara is a pioneer in thoracic oncology and molecular profiling of lung cancer. He has led landmark trials in KRAS-mutant NSCLC and championed the use of biomarker-driven therapy selection. His work on sotorasib in CodeBreaK trials established sotorasib as the first approved KRAS G12C inhibitor. He has contributed extensively to understanding resistance mechanisms in KRAS-mutant lung cancer.

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🧪Research Fields 研究领域

KRAS NSCLC
lung cancer biomarkers
CodeBreaK trial
sotorasib
immunotherapy combinations

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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