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Translational Medicine / 转化医学Neuro-Oncology, IDH Mutant Glioma

David Cahill

MD, PhD

🏢Massachusetts General Hospital🌐USA

Associate Professor, Department of Neurosurgery

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👥Biography 个人简介

David Cahill is a neurosurgeon-scientist focused on IDH-mutant diffuse gliomas. His laboratory studies the oncogenic mechanisms of IDH mutations including 2-hydroxyglutarate production and its effects on epigenetic reprogramming. He has conducted early-phase trials of IDH inhibitors in recurrent IDH-mutant glioma and contributed to understanding the natural history of transformation from low-grade to high-grade IDH-mutant glioma.

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🧪Research Fields 研究领域

IDH mutant glioma biology
IDH inhibitors glioma
low-grade glioma transformation
2-hydroxyglutarate IDH
diffuse glioma natural history

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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