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Translational Medicine / 转化医学In Situ Vaccination and Intratumoral Therapy

Diwakar Davar

MD

🏢UPMC Hillman Cancer Center🌐USA

Associate Professor of Medicine

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Key Contributions

👥Biography 个人简介

Diwakar Davar has conducted groundbreaking clinical trials combining intratumoral immune agonists with microbiome-based therapies to overcome checkpoint inhibitor resistance. His work on fecal microbiota transplant plus anti-PD-1 demonstrated that microbiome modulation can restore immunotherapy sensitivity. He has advanced intratumoral SD-101 (CpG TLR9 agonist) clinical trials in combination with systemic immunotherapy.

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🧪Research Fields 研究领域

Intratumoral microbiome therapy
FMT immunotherapy combinations
SD-101 TLR9 agonist
Melanoma intratumoral therapy
Gut-tumor immune axis

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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