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Translational Medicine / 转化医学Regulatory T Cells, LAG-3 IL-35
Dario Vignali
PhD
🏢University of Pittsburgh / UPMC Hillman🌐USA
Vice Chair and Professor of Immunology
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Key Papers
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Key Contributions
👥Biography 个人简介
Dario Vignali identified IL-35 as an inhibitory cytokine produced by regulatory T cells and defined neuropilin-1 as a marker of Treg stability. His work on LAG-3 biology contributed to the development of relatlimab. He leads immunology at the UPMC Hillman Cancer Center.
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🧪Research Fields 研究领域
LAG-3 Treg
IL-35 inhibitory cytokine
NRP1 Treg fragility
checkpoint Treg
Treg metabolism
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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