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Translational Medicine / 转化医学Global Oncology

Daniela Sprinz

丹妮拉·斯普林茨

MD, PhD

🏢Hospital de Clínicas de Porto Alegre (HCPA)(阿雷格里港临床医院)🌐Brazil

Head of Oncology & HIV-Associated Malignancies Program肿瘤科主任兼HIV相关恶性肿瘤项目负责人

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Daniela Sprinz is a leading expert on HIV-associated malignancies in Latin America, heading HCPA's oncology program in Porto Alegre. She has built one of Brazil's largest HIV-cancer cohorts and contributed seminal research on AIDS-defining and non-AIDS-defining cancers in the era of antiretroviral therapy.

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🧪Research Fields 研究领域

HIV-Associated MalignanciesHIV相关恶性肿瘤
Infectious Disease Oncology感染性疾病肿瘤学
Latin America Cancer Care拉丁美洲癌症医疗

🎓Key Contributions 主要贡献

HIV-Associated Cancer Research

Established Brazil's most comprehensive HIV-cancer registry, enabling longitudinal studies on cancer incidence, treatment outcomes, and antiretroviral interactions in HIV-positive patients.

Non-AIDS-Defining Cancer Management

Pioneered clinical protocols for managing non-AIDS-defining cancers (lung, anal, liver) in PLWH in Brazil, adopted as national guidance by the Brazilian Ministry of Health.

Antiretroviral-Chemotherapy Interactions

Conducted pharmacokinetic studies on interactions between antiretroviral agents and oncology drugs, directly improving safety of concurrent HIV and cancer treatment.

Representative Works 代表性著作

[1]

Cancer incidence in HIV-infected patients in Brazil in the antiretroviral therapy era

HIV Medicine (2020)

Large cohort study quantifying cancer incidence trends in Brazilian PLWH over 15 years, showing rising non-AIDS-defining cancers despite viral suppression.

[2]

Anal cancer in HIV-positive patients in Brazil: clinical characteristics and outcomes

International Journal of STD & AIDS (2019)

First national study on anal squamous cell carcinoma in Brazilian HIV-positive patients, highlighting late-stage diagnosis and poor outcomes.

[3]

Drug interactions between antiretrovirals and chemotherapy: a systematic review for clinical practice

Cancer Treatment Reviews (2021)

Comprehensive systematic review providing practical guidance on managing antiretroviral-chemotherapy drug interactions, widely adopted in oncology and infectious disease practice.

🏆Awards & Recognition 奖项与荣誉

🏆Brazilian Infectious Diseases Society Research Award
🏆HCPA Excellence in Clinical Research Prize
🏆International AIDS Society Young Investigator Recognition

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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