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Translational Medicine / 转化医学Targeted Therapy Pioneers, ALK Inhibitors

D. Ross Camidge

MB BChir, PhD

🏢University of Colorado Cancer Center🌐USA

Joyce Zeff Chair in Lung Cancer Research

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👥Biography 个人简介

D. Ross Camidge at the University of Colorado has been central to the clinical development of ALK inhibitors including crizotinib, alectinib, and next-generation ALK inhibitors for ALK-rearranged NSCLC. He contributed to the PROFILE clinical trials that established crizotinib and contributed to the development of brigatinib and lorlatinib. His research on ALK inhibitor resistance mechanisms and optimal treatment sequencing has helped define treatment algorithms for ALK-positive lung cancer. His comprehensive clinical research spanning ALK, ROS1, and other oncogenic fusions in lung cancer has advanced precision oncology for this disease.

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🧪Research Fields 研究领域

ALK inhibitors crizotinib alectinib
ALK rearrangement NSCLC targeted therapy
brigatinib lorlatinib ALK clinical trials
ALK inhibitor resistance mechanisms
PROFILE trials crizotinib lung

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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