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Translational Medicine / 转化医学CAR-T Therapy, GD2 Neuroblastoma

Crystal Mackall

MD

🏢Stanford University School of Medicine🌐USA

Director, Stanford Center for Cancer Cell Therapy

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👥Biography 个人简介

Crystal Mackall is a pioneering researcher in CAR-T cell therapies for pediatric solid tumors with a focus on GD2-targeting for neuroblastoma. Her laboratory has made seminal contributions to understanding T cell exhaustion in the context of cancer immunotherapy. She has developed strategies to prevent CAR-T exhaustion and enhance persistence in solid tumors. Her translational work has advanced multiple CAR-T constructs from bench to clinical trials.

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🧪Research Fields 研究领域

GD2 CAR-T
neuroblastoma
pediatric oncology
T cell exhaustion
solid tumor CAR-T

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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