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Translational Medicine / 转化医学Cancer Antisense Oligonucleotides

Stanley Crooke

MD, PhD

🏢Ionis Pharmaceuticals🌐USA

Founder and Chair, n-Lorem Foundation; Founder, Ionis Pharmaceuticals

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👥Biography 个人简介

Stanley Crooke founded Ionis Pharmaceuticals and pioneered the antisense oligonucleotide therapeutic field. His work established the chemistry, pharmacology, and clinical translation of ASOs for cancer and genetic disease. He founded the n-Lorem Foundation for individualized ASO therapy.

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🧪Research Fields 研究领域

antisense oligonucleotides
RNase H mechanism
ASO chemistry
cancer ASO therapy
phosphorothioate backbone

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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