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Translational Medicine / 转化医学Cancer Prevention Milestones

Pelayo Correa

MD

🏢Vanderbilt University🌐USA

Professor Emeritus of Pathology (historical Correa cascade pioneer)

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Key Contributions

👥Biography 个人简介

Pelayo Correa defined the Correa cascade describing the stepwise progression from chronic gastritis through intestinal metaplasia to gastric adenocarcinoma, providing the biological rationale for Helicobacter pylori eradication as gastric cancer prevention. His epidemiological studies in Colombia identified environmental and dietary risk factors that modify gastric cancer risk at each stage of the cascade. His work has informed global gastric cancer prevention strategies including H. pylori screening and eradication programs.

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🧪Research Fields 研究领域

Correa cascade of gastric carcinogenesis
H. pylori and gastric cancer
Gastric cancer prevention
Intestinal metaplasia progression
Chemoprevention of gastric cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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