Ryan Corcoran

Ryan Corcoran has been at the forefront of using serial ctDNA measurements to track treatment response and resistance evolution in colorectal and other gastrointestinal cancers, with his work directly informing MRD-guided therapy strategies. His research on RAS and RAF mutation dynamics in ctDNA has provided real-time insights into how resistance emerges and can be intercepted through adaptive therapy approaches. He leads clinical trials using MRD detection to guide adjuvant and maintenance therapy decisions.