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Translational Medicine / 转化医学Mitochondrial UPR, ATFS-1 Pioneer
Cole Haynes
PhD
🏢UMass Chan Medical School🌐USA
Professor of Molecular, Cell and Cancer Biology
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Key Contributions
👥Biography 个人简介
Cole Haynes pioneered the mitochondrial unfolded protein response (mtUPR), identifying ATFS-1 as a key transducer in C. elegans. His work defined how mitochondrial proteostasis stress is communicated to the nucleus. He extends mtUPR biology into cancer cell physiology.
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🧪Research Fields 研究领域
mitochondrial unfolded protein response
ATFS-1
C. elegans
mitochondrial stress
cancer metabolism
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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