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Translational Medicine / 转化医学Phase Separation, Biomolecular Condensates

Clifford Brangwynne

PhD

🏢Princeton University🌐USA

Professor of Chemical and Biological Engineering

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Key Contributions

👥Biography 个人简介

Clifford Brangwynne is a pioneer in the field of biological phase separation, demonstrating that P granules and other cellular bodies form through liquid-liquid phase separation. His work has fundamentally reshaped understanding of intracellular organization and has profound implications for cancer biology, where aberrant condensate formation drives oncogenic transcription and drug resistance. He received the MacArthur Fellowship and Breakthrough Prize for his contributions.

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🧪Research Fields 研究领域

phase separation biology
biomolecular condensates
intrinsically disordered regions
membraneless organelles
biophysics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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