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Translational Medicine / 转化医学Tumor Initiation, Intestinal Stem Cells
Hans Clevers
MD, PhD
🏢Roche and Hubrecht Institute🌐Netherlands
Head, Roche Pharma Research and Early Development
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Key Papers
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Key Contributions
👥Biography 个人简介
Hans Clevers discovered LGR5 as a marker of intestinal stem cells and established organoid culture systems that transformed cancer modeling. His work traced colorectal cancer origins to stem cells in the crypt. He leads research at Roche pRED while continuing his organoid program.
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🧪Research Fields 研究领域
LGR5 stem cells
organoids
Wnt signaling
intestinal cancer
tumor initiation
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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