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Translational Medicine / 转化医学Cancer Antisense Oligonucleotides

Don Cleveland

PhD

🏢University of California, San Diego🌐USA

Distinguished Professor of Medicine, Neurosciences, and Cellular and Molecular Medicine

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Key Contributions

👥Biography 个人简介

Don Cleveland pioneered antisense oligonucleotide therapy for ALS and other neurodegenerative diseases including the development of tofersen. His work established CNS delivery of ASOs and has implications for brain tumor ASO therapy. He is a leading figure in ASO neurotherapeutics.

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🧪Research Fields 研究领域

ALS ASO therapy
tofersen
neurodegeneration
cancer ASO
microtubule biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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