Claus Azzalin
PhD
Principal Investigator
👥Biography 个人简介
Claus Azzalin discovered TERRA (telomeric repeat-containing RNA), the long non-coding RNA transcribed from telomeres that plays critical roles in telomere maintenance and ALT pathway activation. His work showed that TERRA forms R-loops at telomeres, promoting recombination-based telomere lengthening in ALT-positive cancers. He has revealed how TERRA regulates telomere heterochromatin and the DNA damage response at chromosome ends.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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