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Translational Medicine / 转化医学Mucinous Ovarian Cancer, KRAS Targeted Therapy

Clare Scott

MBBS, PhD, FRACP

🏢Walter and Eliza Hall Institute of Medical Research🌐Australia

Professor, Walter and Eliza Hall Institute

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Key Contributions

👥Biography 个人简介

Clare Scott is a medical oncologist whose translational research has characterized the distinct biology of mucinous ovarian carcinoma — an entity with worse outcomes on standard platinum-paclitaxel and fundamentally different from high-grade serous ovarian cancer. Her group has demonstrated high KRAS G12D mutation prevalence and HER2 amplification in mucinous ovarian cancer, providing rationale for KRAS-targeted and HER2-directed therapies. She leads Australian ovarian cancer clinical trials and advocates for histotype-specific clinical trial designs rather than lumping all ovarian cancers together.

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🧪Research Fields 研究领域

mucinous ovarian carcinoma treatment KRAS
mucinous ovarian different from serous
KRAS G12D mucinous ovarian
HER2 amplification mucinous ovarian
ovarian cancer histotype-specific therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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