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Translational Medicine / 转化医学CAR-T Therapy, IL13Ra2 GBM

Christine Brown

PhD

🏢City of Hope National Medical Center🌐USA

Professor and Director, T Cell Immunotherapy

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👥Biography 个人简介

Christine Brown is a leading scientist in IL13Ra2-targeted CAR-T therapy for glioblastoma at City of Hope. Her groundbreaking work demonstrated the first case of complete tumor regression in a recurrent GBM patient treated with IL13Ra2 CAR-T cells delivered locoregionally. She has developed sophisticated manufacturing protocols for brain tumor CAR-T therapies. Her research continues to optimize delivery routes and CAR-T construct design for central nervous system tumors.

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🧪Research Fields 研究领域

IL13Ra2 CAR-T
glioblastoma
brain tumor immunotherapy
locoregional therapy
CAR-T persistence

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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