Christian Gisselbrecht

Christian Gisselbrecht at Saint-Louis conducted the landmark CORAL study comparing R-ICE versus R-DHAP salvage chemotherapy in relapsed DLBCL before autologous transplant — demonstrating equivalent efficacy but differential benefit by molecular subtype (ABC vs. GCB). This analysis drove the hypothesis that subtype-guided salvage therapy selection is important and remains relevant as CAR-T therapies are integrated into the relapsed DLBCL treatment landscape.