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Translational Medicine / 转化医学Biomarkers

Charles Swanton

M.D., Ph.D., FRCP, FMedSci, FRS

🏢Francis Crick Institute / UCL Cancer Institute🌐United Kingdom

Group Leader; Chief Clinician, Cancer Research UK

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Charles Swanton is a world leader in understanding tumor evolution and heterogeneity. His TRACERx study is a landmark prospective cohort study tracking lung cancer evolution from diagnosis through treatment and relapse. Swanton's work on chromosomal instability and tumor phylogenetics has transformed understanding of cancer progression and resistance.

Charles Swanton是理解肿瘤进化和异质性的世界领导者。他的TRACERx研究是一项里程碑式的前瞻性队列研究,追踪肺癌从诊断到治疗和复发的进化。Swanton在染色体不稳定性和肿瘤系统发育方面的工作改变了对癌症进展和耐药性的理解。

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🧪Research Fields 研究领域

Tumor Evolution肿瘤进化
Intratumor Heterogeneity肿瘤内异质性
Lung Cancer肺癌

🎓Key Contributions 主要贡献

TRACERx Study

Leading longitudinal study of lung cancer evolution tracking intratumor heterogeneity.

Chromosomal Instability

Characterized CIN as driver of tumor evolution and drug resistance.

Representative Works 代表性著作

[1]

Tracking the Evolution of Non-Small-Cell Lung Cancer

New England Journal of Medicine (2017)

TRACERx prospective cohort study.

🏆Awards & Recognition 奖项与荣誉

🏆Fellow of the Royal Society (2020)
🏆AACR Team Science Award (2020)

📄Data Sources 数据来源

Last updated: 2026-03-05 | All information from publicly available academic sources

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