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Translational Medicine / 转化医学Prostate Cancer, Enzalutamide

Charles Ryan

MD

🏢University of Minnesota🌐USA

Hematology and Oncology Division Director

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Key Papers
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Key Contributions

👥Biography 个人简介

Charles Ryan led the PREVAIL trial demonstrating enzalutamide's benefit in chemotherapy-naive metastatic castration-resistant prostate cancer, contributing to its FDA approval and establishing it as a first-line standard. His foundational research on androgen receptor biology and resistance mechanisms in CRPC has shaped the treatment landscape for advanced prostate cancer.

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🧪Research Fields 研究领域

prostate cancer
enzalutamide
PREVAIL trial
androgen receptor signaling
castration-resistant prostate cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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