Charles Rudin
MD, PhD
Chief, Thoracic Oncology Service
👥Biography 个人简介
Charles Rudin is the world's foremost expert on small cell lung cancer (SCLC) biology and therapy. His laboratory identified transcription factor-based SCLC subtypes (ASCL1, NEUROD1, POU2F3, YAP1) that have fundamentally reorganized understanding of SCLC heterogeneity and treatment sensitivity. He drove development of DLL3-targeting therapies including rovalpituzumab tesirine and has led multiple pivotal clinical trials for SCLC. His work on SCLC plasticity and neuroendocrine differentiation has opened new research avenues and therapeutic strategies for this devastating malignancy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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