Chad A. Mirkin

Chad Mirkin is the George B. Rathmann Professor of Chemistry at Northwestern University and Director of the International Institute for Nanotechnology. He is one of the most decorated nanoscientists in history, cited by Nature as one of the most influential scientific minds globally. Mirkin invented Spherical Nucleic Acids (SNAs) — densely functionalized nanoparticles with oligonucleotide shells that have unique biological properties including cell entry without transfection agents, immunomodulatory properties, and tumor penetration. SNAs are being developed for cancer, glioblastoma, and immunotherapy applications. He invented Dip-Pen Nanolithography (DPN) — a tool for writing patterns at nanometer scale, and developed the nanoflares detection technology for detecting cancer-related RNAs in live cells. He has founded 12 companies and has over 1,200 patents.

Chad Mirkin 是西北大学乔治·拉斯曼化学教授，也是国际纳米技术研究所所长。他是历史上获奖最多的纳米科学家之一，被《自然》杂志评为全球最具影响力的科学家之一。 Mirkin 发明了球形核酸（SNA）——密集功能化的纳米颗粒，具有寡核苷酸外壳，拥有独特的生物特性，包括无需转染试剂的细胞进入、免疫调节特性和肿瘤穿透能力。SNA正在被开发用于癌症、胶质母细胞瘤和免疫治疗应用。