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Translational Medicine / 转化医学Neoantigen Vaccine, Personalized Immunotherapy

Catherine Wu

MD

🏢Dana-Farber Cancer Institute / Harvard Medical School🌐USA

Professor of Medicine

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Key Contributions

👥Biography 个人简介

Catherine Wu pioneered the development of personalized neoantigen vaccines, demonstrating in landmark clinical trials that vaccination against patient-specific tumor neoantigens presented on MHC molecules can generate robust anti-tumor T cell responses. Her NeoVax platform for melanoma showed durable complete responses and has been extended to glioblastoma and other cancer types. She has established the feasibility of individualized cancer vaccination targeting MHC-presented neoantigens.

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🧪Research Fields 研究领域

neoantigen vaccine
personalized cancer vaccine
NeoVax platform
melanoma vaccination
CLL neoantigen

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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