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Cell Therapy / 细胞治疗TIL

Cassian Yee

M.D.

🏢MD Anderson Cancer Center🌐USA

Professor, Department of Melanoma Medical Oncology

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Key Papers
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Key Contributions

👥Biography 个人简介

Cassian Yee is a leader in developing personalized T cell therapies for cancer. His research focuses on isolating and expanding tumor-reactive T cells from patients, including both TILs and peripheral blood-derived T cells targeting specific tumor antigens. Yee has advanced manufacturing approaches that enhance T cell fitness and persistence for improved clinical outcomes.

Cassian Yee是开发个性化T细胞癌症治疗的领导者。他的研究专注于从患者中分离和扩增肿瘤反应性T细胞,包括TIL和靶向特定肿瘤抗原的外周血来源T细胞。Yee推进了增强T细胞适应性和持久性的制造方法,以改善临床结果。

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🧪Research Fields 研究领域

T Cell TherapyT细胞治疗
Tumor-Infiltrating Lymphocytes肿瘤浸润淋巴细胞
Melanoma Immunotherapy黑色素瘤免疫治疗

🎓Key Contributions 主要贡献

Antigen-Specific T Cells

Developed methods for isolating and expanding tumor antigen-specific T cells from patients.

T Cell Manufacturing

Advanced manufacturing protocols to enhance T cell fitness and in vivo persistence.

Representative Works 代表性著作

[1]

Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma

Nature Medicine (2002)

Early demonstration of antigen-specific adoptive T cell therapy.

📄Data Sources 数据来源

Last updated: 2026-03-04 | All information from publicly available academic sources

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