Stephanie Gaillard
斯蒂芬妮·盖拉德
MD, PhD
Associate Professor of Gynecologic Oncology妇科肿瘤学副教授
👥Biography 个人简介
Stephanie Gaillard is a gynecologic oncologist and translational researcher at Johns Hopkins who focuses on early carcinogenesis in fallopian tube cancer and novel therapeutic strategies beyond PARP inhibitors for ovarian cancer. Her laboratory studies BRCA1/2-associated fallopian tube precursor lesions (STICs) as origins of high-grade serous ovarian cancer, and she leads clinical trials of CDK4/6 inhibitors and WEE1 inhibitors in recurrent ovarian cancer. Gaillard has contributed to NRG Oncology trials and is developing ctDNA-based early detection strategies for ovarian cancer in high-risk BRCA mutation carriers.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Fallopian Tube Carcinogenesis Research
Characterized STICs (serous tubal intraepithelial carcinomas) as precursors of high-grade serous ovarian cancer, advancing understanding of disease origins and identifying opportunities for interception in high-risk women.
Novel Cell Cycle Inhibitors in Ovarian Cancer
Led clinical trials of CDK4/6 and WEE1 inhibitors in platinum-resistant ovarian cancer, identifying biomarkers of response and rational combination strategies with DNA-damaging agents.
Representative Works 代表性著作
Clinical Activity of Adavosertib (WEE1 Inhibitor) in Combination with Olaparib in Recurrent Ovarian Cancer
Clinical Cancer Research (2020)
Phase I/II trial of WEE1 plus PARP inhibition in ovarian cancer.
STICs as Precursors of BRCA-Associated Ovarian Cancer
Gynecologic Oncology (2017)
Characterization of serous tubal intraepithelial carcinomas in BRCA carriers.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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Drew M. Pardoll
Johns Hopkins University
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Naiyer A. Rizvi
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