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Translational Medicine / 转化医学Melanoma PD-1 Therapy, Adjuvant Pembrolizumab

Caroline Robert

MD, PhD

🏢Institut Gustave Roussy🌐France

Head of Dermatology and Chief of Cancer Medicine Department

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👥Biography 个人简介

Caroline Robert is a globally recognized melanoma expert who co-led the KEYNOTE-054 phase III trial establishing adjuvant pembrolizumab as a standard of care for resected high-risk stage III melanoma. Her research demonstrated that adjuvant pembrolizumab significantly improves recurrence-free survival compared to placebo in patients with resected stage IIIA-IIIC melanoma. She has investigated predictive biomarkers for adjuvant pembrolizumab benefit and long-term outcomes data from KEYNOTE-054 showing durable protection from recurrence. Her contributions to melanoma immunotherapy span from early pembrolizumab development through contemporary adjuvant and neoadjuvant strategies.

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🧪Research Fields 研究领域

pembrolizumab melanoma
adjuvant immunotherapy melanoma
KEYNOTE-054 trial
anti-PD-1 therapy
advanced melanoma treatment

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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