Carlos Rodriguez-Galindo
卡洛斯·罗德里格斯-加林多
MD
Executive Vice President and Scientific Director; Chair, Department of Global Pediatric Medicine; Member, Department of Oncology执行副总裁兼科学主任，全球儿童医学系主任
👥Biography 个人简介
Carlos Rodriguez-Galindo, MD is Executive Vice President and Scientific Director of St. Jude Children's Research Hospital and one of the foremost authorities on retinoblastoma and global pediatric oncology. He led the development and clinical validation of intra-arterial chemotherapy (ophthalmic artery chemosurgery, OAC) as a globe-salvaging treatment for retinoblastoma, dramatically reducing the need for enucleation in patients with advanced intraocular disease. He also spearheaded the St. Jude Global Alliance initiative, which has partnered with childhood cancer centers in more than 50 low- and middle-income countries to improve childhood cancer survival through capacity building, training, and protocol implementation. His dual focus on innovative treatment development and equitable global access has made him a transformative figure in international pediatric oncology.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Intra-Arterial Chemotherapy for Retinoblastoma
Pioneered and validated ophthalmic artery chemosurgery (OAC) with melphalan as a primary globe-salvaging therapy for advanced group D and E retinoblastoma, achieving eye salvage rates of over 70% and establishing OAC as a new standard of care.
St. Jude Global Alliance for Childhood Cancer
Founded and directs the St. Jude Global Alliance, partnering with 190+ hospitals in 50+ low- and middle-income countries to close the childhood cancer survival gap through protocol sharing, training fellowships, and telemedicine support.
Risk Stratification and Staging of Retinoblastoma
Contributed to the development and validation of the International Intraocular Retinoblastoma Classification (IIRC) and International Retinoblastoma Staging System (IRSS), standardizing global risk assessment and enabling collaborative trial design.
Systemic Chemoreduction in Retinoblastoma
Defined protocols for systemic carboplatin/vincristine/etoposide chemoreduction combined with focal consolidation for bilateral retinoblastoma, enabling preservation of vision and both eyes in the majority of young patients.
Representative Works 代表性著作
Ophthalmic artery chemosurgery for the management of advanced retinoblastoma: the St Jude Children's Research Hospital experience
Archives of Ophthalmology (2010)
Early experience with OAC at St. Jude demonstrating high globe salvage rates with acceptable toxicity in advanced-group retinoblastoma.
Global challenges in the diagnosis and treatment of retinoblastoma
Annals of Oncology (2021)
Comprehensive analysis of barriers to retinoblastoma care in low- and middle-income countries and strategies to improve outcomes through the St. Jude Global Alliance framework.
Childhood cancer in low- and middle-income countries: an SIOP PODC review
Pediatric Blood & Cancer (2021)
Systematic assessment of the global childhood cancer burden and evidence-based strategies for improving access, early diagnosis, and treatment in resource-limited settings.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-04-06 | All information from publicly available academic sources
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