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Translational Medicine / 转化医学Global Oncology

Carlos Barrios

卡洛斯·巴里奥斯

MD

🏢Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) / ESMO Latin America(南里奥格兰德州天主教大学 / 欧洲肿瘤学会拉丁美洲区)🌐Brazil

Director, Oncology Research Center & ESMO Latin America Chair肿瘤研究中心主任兼欧洲肿瘤学会拉丁美洲主席

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Key Papers
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Key Contributions

👥Biography 个人简介

Carlos Barrios is one of Latin America's most prominent breast cancer trialists, directing PUCRS's oncology research center in Porto Alegre. As ESMO Latin America Chair, he has bridged European and Latin American oncology communities, led groundbreaking trials in HER2+ and triple-negative breast cancer, and trained a generation of Brazilian oncologists.

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🧪Research Fields 研究领域

Breast Cancer乳腺癌
Clinical Trials临床试验
Global Oncology全球肿瘤学

🎓Key Contributions 主要贡献

Breast Cancer Clinical Trials

Principal investigator for landmark trials including CLEOPATRA, EMILIA, and MARIANNE, making PUCRS one of the highest-enrolling Latin American sites in global HER2+ breast cancer studies.

ESMO Latin America Leadership

As ESMO Latin America Chair, established regional educational programs, guideline adaptations, and fellowship schemes that have trained 500+ oncologists across the region.

Real-World Evidence Generation

Led Brazilian and Latin American real-world evidence studies on breast cancer outcomes, treatment patterns, and access disparities informing national health policy.

Representative Works 代表性著作

[1]

Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer (CLEOPATRA): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study

The Lancet Oncology (2015)

Pivotal phase III trial establishing pertuzumab+trastuzumab as first-line standard of care in HER2+ mBC; Barrios was a key PI for Latin American sites.

[2]

Breast cancer in Latin America: current situation and future perspectives

Breast (2018)

Comprehensive review of breast cancer epidemiology, treatment access, and research capacity across Latin America with actionable recommendations.

[3]

Trastuzumab emtansine (T-DM1) versus capecitabine plus lapatinib in HER2-positive metastatic breast cancer (EMILIA): a descriptive analysis of final overall survival results

The Lancet Oncology (2017)

Final OS analysis of the EMILIA trial confirming long-term survival benefit of T-DM1 in previously treated HER2+ mBC.

🏆Awards & Recognition 奖项与荣誉

🏆ESMO Distinguished Service Award
🏆SBOC Oncologist of the Year
🏆ASCO Special Recognition for Global Oncology Contributions

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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