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Translational Medicine / 转化医学CAR-T Engineering, Immunotherapy Pioneer

Carl June

MD

🏢University of Pennsylvania🌐USA

Richard W. Vague Professor in Immunotherapy

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Key Contributions

👥Biography 个人简介

Carl June is the pioneer of CAR-T cell therapy at the University of Pennsylvania, having developed the first clinically successful CD19-targeted CAR-T cells for B cell malignancies. His laboratory continues to engineer next-generation CAR constructs including armored CARs and gene-edited universal CAR-T cells. His foundational work has transformed hematologic oncology and catalyzed the broader CAR-T industry.

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🧪Research Fields 研究领域

CAR-T cell engineering
CD19 CAR-T
solid tumor CAR-T
gene editing CAR
T cell therapy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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