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Translational Medicine / 转化医学X-Inactivation Skewing, Clonal Hematopoiesis

Lambert Busque

MD, FRCPC

🏢Hopital Maisonneuve-Rosemont, Universite de Montreal🌐Canada

Hematologist and Professor

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Key Contributions

👥Biography 个人简介

Lambert Busque performed early work defining skewed X-inactivation as a marker of clonal hematopoiesis in aging women, well before the CHIP era. He later linked TET2 mutations to age-related clonal expansion. He continues to investigate genetic and epigenetic drivers of clonal hematopoiesis.

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🧪Research Fields 研究领域

clonal hematopoiesis
X-inactivation
aging hematopoiesis
TET2
hematologic disease

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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