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Translational Medicine / 转化医学CAR-T Therapy, Glioblastoma

Bryan Bhatt

MD

🏢University of California San Francisco🌐USA

Associate Professor of Neurosurgery and Oncology

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👥Biography 个人简介

Bryan Bhatt specializes in CAR-T cell therapy targeting EGFRvIII in glioblastoma, a mutation expressed exclusively in tumor cells. His work addresses the unique challenges of delivering cell therapies across the blood-brain barrier and within the immunosuppressive glioma microenvironment. He has pioneered locoregional delivery approaches for CAR-T cells in brain tumors. His clinical research has shown that intracranial CAR-T delivery can achieve responses in recurrent GBM.

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🧪Research Fields 研究领域

EGFRvIII CAR-T
glioblastoma
brain tumor immunotherapy
intracranial delivery
neuro-oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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