Bruce Levine
布鲁斯·莱文
PhD
Barbara and Edward Netter Professor in Cancer Gene Therapy芭芭拉与爱德华·内特尔癌症基因治疗教授
👥Biography 个人简介
Leading authority on GMP-compliant manufacturing of CAR-T cell therapies. Co-inventor of lentiviral vector-based CAR-T manufacturing platforms that enabled clinical translation of tisagenlecleucel (Kymriah), the first FDA-approved CAR-T therapy.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
CAR-T GMP Manufacturing
Developed scalable lentiviral transduction and GMP manufacturing protocols for CAR-T cells that underpinned the clinical and commercial production of tisagenlecleucel.
Representative Works 代表性著作
Global manufacturing of CAR T cell therapy
Molecular Therapy Methods & Clinical Development (2016)
Defined global standards and technical requirements for scalable GMP manufacturing of CAR-T cell products.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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University of Pennsylvania
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